School of medicine

School Notes: School of Medicine
March/April 2022

Nancy J. Brown | http://medicine.yale.edu

Department of Pediatrics celebrates 100 years of excellence

The Department of Pediatrics, founded in 1921, is commemorating 100 years of providing top-quality care for children and training the next generation of pediatric leaders.

“Throughout the history of the Department of Pediatrics, we have met the vision we have established—which is being healers, innovators, and collaborators, and leading worldwide in improving the health of children and adolescents,” said Clifford Bogue, chair and Waldemar Von Zedtwitz Professor of Pediatrics, at the Pediatric Centennial Kickoff held on September 15. “That vision is built on the shoulders of all the giants that came before us.”

In honor of its 100th anniversary, the department is holding a series of events throughout the year, which included an endocrine/obesity/diabetes symposium in November. A full list of past and upcoming events can be found on the Department of Pediatrics website. 

Nasal vaccination may protect better than injected vaccines

A Yale School of Medicine research team led by Akiko Iwasaki, Waldemar Von Zedtwitz Professor of Immunobiology and professor of molecular, cellular, and developmental biology and of epidemiology (microbial diseases), has found that local vaccines administered with a nasal spray were more effective in protecting mice against influenza than vaccines that are injected into the muscle, the way standard flu shots are done. This mucosal vaccine, says Iwasaki, prevents the virus from invading the body by “putting the guard outside of the door instead of inside the door where antibodies normally work.” 

The team published their findings on December 10 in Science Immunology. They are now using animal models to test nasal vaccines against COVID-19 strains. Iwasaki believes that if nasal vaccines prove to be safe and efficient in humans, they will be a useful supplement to the existing vaccines against COVID and ease the fears of individuals afraid of the needle. 

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