Yale research may point the way to a new melanoma treatment. An enzyme called DNMT3b is known to lead to melanoma growth. In a study published online in Cell Reports, dermatology researcher Marcus Bosenberg and his colleagues have now established exactly how that happens. The breakthrough could help scientists develop better cancer therapies.

To restore sections of a work by eighteenth-century Venetian painter Canaletto—Old Walton Bridge (1755), in the Yale Center for British Art—Roxane Sperber, then a conservation fellow, worked with Jens Stenger, an associate conservation scientist, at Yale’s Institute for the Preservation of Cultural Heritage. Analysis revealed that during the decade he spent in London, Canaletto had started working with blue verditer, a new color not in his Venetian paint box. The finding disproves the impression among art historians that Canaletto never changed his pigments.

By pushing NASA’s Hubble Space Telescope beyond its supposed limits, a team led by Pascal Oesch, a postdoc in Yale’s astronomy and physics departments, has spotted the most distant galaxy yet known. Using techniques developed at Yale, Oesch’s group discovered that light from GN-z11 has been traveling more than 13.4 billion years—dating it to a mere 400 million years after the Big Bang. Oesch’s “major step back in time,” announced in the Astrophysical Journal, provides a glimpse of the formation of the first galaxies.

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